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H-9 hydrochloride

CAS No. 116970-50-4

H-9 hydrochloride ( —— )

产品货号. M21838 CAS No. 116970-50-4

H-9 hydrochloride is a potent and competitive inhibitor of protein kinase C, cAMP-dependent protein kinase, and cGMP.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
10MG ¥684 有现货
50MG ¥2880 有现货
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    H-9 hydrochloride
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    H-9 hydrochloride is a potent and competitive inhibitor of protein kinase C, cAMP-dependent protein kinase, and cGMP.
  • 产品描述
    H-9 hydrochloride inhibits PKA (Ki=1.9 μM), PKC (Ki=18 μM; cGKI (PKG) =0.87 μM; MLCK=70 μM). It has shown to dramatically reduce the GABA response of GABAA currents in retinal rod bipolar cells as well as inhibit smooth muscle cell relaxation induced by cGRP. H-9 dihydrochloride has also been used for purification of protein kinases in ligand affinity chromatography.
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    cGKI
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    116970-50-4
  • 分子量
    287.77
  • 分子式
    C11H13N3O2S?HCl
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    C1=CC2=C(C=CN=C2)C(=C1)S(=O)(=O)NCCN.Cl
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Wolf, M., et al. 1985. J. Biol. Chem. 260: 15718-15722. PMID: 4066694 2. Inagaki, M., et al. 1985. J. Biol. Chem. 260: 2922-2925. PMID: 2982842 3. Gillette, M.A., et al. 1996. J. Neurophysiol. 76: 3070-3086. PMID: 8930256
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