H-9 hydrochloride

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

H-9 Hydrochronide 是一种有效的竞争性蛋白激酶 C、cAMP 依赖性蛋白激酶和 cGMP 抑制剂。

H-9 hydrochloride inhibits PKA (Ki=1.9 μM), PKC (Ki=18 μM; cGKI (PKG) =0.87 μM; MLCK=70 μM). It has shown to dramatically reduce the GABA response of GABAA currents in retinal rod bipolar cells as well as inhibit smooth muscle cell relaxation induced by cGRP. H-9 dihydrochloride has also been used for purification of protein kinases in ligand affinity chromatography.

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Others

Other Targets

cGKI

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116970-50-4

287.77

C11H13N3O2S?HCl

>98% (HPLC)

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C1=CC2=C(C=CN=C2)C(=C1)S(=O)(=O)NCCN.Cl

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(-20℃)

With Ice Pack

≥ 2 years